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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Bleomycin
supplement:
Butylated Hydroxytoluene
Research Papers that Mention the Interaction
“BHA and BHT treatments significantly inhibited lung weight gains by BLM (P < 0.05).”
Inhibitory effects of the dietary antioxidants butylated hydroxyanisole and butylated hydroxytoluene on bronchioloalveolar cell proliferation during the bleomycin-induced pulmonary fibrosing process in hamsters.“ Bleomycin delayed the onset of lung cell proliferation normally seen after treatment with BHT while CP attenuated this cell division only after it had begun.”
“Mice given 100, 75, 50, 40 or 25 mg/kg bleomycin 1 day after BHT exhibited 100, 90, 22, 20 and 21% mortality, respectively.”
“Total lung hydroxyproline content, an index of fibrosis, was significantly increased 14 days after the initial treatment in mice given BHT and 50 mg/kg bleomycin compared to mice treated with BHT, bleomycin or vehicle alone.”
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