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Discover Supplement-Drug Interactions
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Last Updated:
3 years ago
Possible Interaction: Bleomycin and Ascorbate
Share:
drug:
Bleomycin
supplement:
Ascorbate
Research Papers that Mention the Interaction
“
Ascorbate
was faster than other antioxidants in promoting two steps in activation of
bleomycin.
”
“In vitro studies detected a greatly superior ability of
ascorbate
over other cellular reducers to catalyze DSB formation by
bleomycin.
”
Vitamin C increases DNA breaks and suppresses DNA damage‐independent activation of ATM by bleomycin
Free radical biology & medicine • 2019 |
View Paper
“The expression of 151 miRNAs was altered 12 h after
ascorbate
treatment of
BLM cells
in physiological or pharmacological doses.”
Epigenetic Impacts of Ascorbate on Human Metastatic Melanoma Cells
Front. Oncol. • 2014 |
View Paper
“In the presence of
ascorbate
, bleomycin (
BLM
) is converted to a redox-inactive form that is incapable of inducing DNA strand scission.”
EPR spin trapping of free radicals produced by bleomycin and ascorbate.
Free radical research communications • 1993 |
View Paper
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