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Last Updated: 3 years ago

Possible Interaction: Bleomycin and Ascorbate

supplement:

Ascorbate

Research Papers that Mention the Interaction

Ascorbate was faster than other antioxidants in promoting two steps in activation of bleomycin.
In vitro studies detected a greatly superior ability of ascorbate over other cellular reducers to catalyze DSB formation by bleomycin.
Free radical biology & medicine  •  2019  |  View Paper
The expression of 151 miRNAs was altered 12 h after ascorbate treatment of BLM cells in physiological or pharmacological doses.
Front. Oncol.  •  2014  |  View Paper
In the presence of ascorbate , bleomycin ( BLM ) is converted to a redox-inactive form that is incapable of inducing DNA strand scission.
Free radical research communications  •  1993  |  View Paper