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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Biotin
drug:
Probenecid
Research Papers that Mention the Interaction
“Inhibition of the biotin uptake (25 μmol/l) was observed in the presence of 250 μmol/l dethiobiotin, bisnorbiotin, thioctic acid, and probenecid , whereas biocytin, propionic acid, lactic acid, succinic acid, citric acid, ascorbic acid, primidone and carbamazepine had no effect.”
Na+-dependent biotin transport into brush-border membrane vesicles from human kidney cortex“Desthiobiotin, 250 microM, norbiotin, bisnorbiotin, thioctic acid, valeric acid, probenecid , and nonanoic acid inhibited the transport of 30 microM biotin , whereas other biotin derivatives, as well as biocytin and organic acids found in the urine of biotinidase-deficient patients, did not.”
Na(+)-dependent biotin transport into brush-border membrane vesicles from rat kidney.
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