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“The nifedipine and the flunarizine, well-known Ca++ -antagonists, have constantly reduced or even abolished the facilitating effect induced by the bioflavonoid.”
Acta vitaminologica et enzymologica • 1985 | View Paper
“The apparent Km for the … activity is inhibited by Ca+2 ; Mn+2 can replace Mg+2 with an increase in the Km for ATP from 47 /… was not affected by cyclic AMP but was inhibited in dose dependent manner by quercetin, a bioflavonoid which is known … in vitro.”