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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Biochanin A
drug:
Tetraethylammonium
Research Papers that Mention the Interaction
“Glibenclamide (3 x 10(-6) mol/L), a … inhibitor of ATP-sensitive potassium channels, and tetraethylammonium (5 x 10(-3) mol/L), a Ca2+ -activated …+ channel inhibitor, significantly attenuated the relaxation induced by biochanin A. The vasoconstriction induced by phenylephrine was decreased by biochanin A in Ca2+ -free medium.”
[Endothelium-independent vasorelaxation of plant-derived estrogen biochanin A and its mechanism in rat aortic rings].“Conversely, treatment with 4‐aminopyridine, a selective inhibitor of voltage‐dependent potassium channels, or tetraethylammonium , an inhibitor of calcium‐activated potassium channels, significantly reduced the vasorelaxation induced by biochanin A in rings from SHR but not WKY rats.”
“By contrast, treatment with glibenclamide, a selective inhibitor of adenosine triphosphate-sensitive K+ channels, or tetraethylammonium , an inhibitor of Ca2+-activated K+ channels, significantly reduced biochanin A-induced relaxation in aortic rings from both groups.”
Mechanisms of phytoestrogen biochanin A-induced vasorelaxation in renovascular hypertensive rats
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