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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Biochanin A and Paclitaxel

supplement:

Biochanin A

Research Papers that Mention the Interaction

In contrast to the in vitro results, intraperitoneal or oral administration of biochanin A did not significantly change the pharmacokinetics of doxorubicin and cyclosporine A. Moderate interaction was observed between biochanin A and paclitaxel , resulting in lower AUC values after both i.v.
Journal of pharmaceutical sciences  •  2010  |  View Paper
With BA coadministration, the oral bioavailability and peak plasma concentration were markedly increased by 3.77- and 2.04-fold for paclitaxel , 1.75- and 1.71-fold for digoxin, but were reduced by 0.694- and 0.429-fold for fexofenadine, respectively.
Journal of pharmaceutical sciences  •  2006  |  View Paper