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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Bilberry Extract and Doxorubicin Hydrochloride

Research Papers that Mention the Interaction

Pretreatment with bilberry significantly guarded against DOX-induced increase in serum activities of lactate dehydrogenase, creatine phosphokinase and creatine kinase-MB, as well as the level of troponin I. Bilberry alleviated ECG changes in rats treated with DOX and attenuated its pathological changes.
Medical science monitor : international medical journal of experimental and clinical research  •  2011  |  View Paper
Although the protective effects of BE were insufficient to completely counteract the toxic effects of Dox , these results suggest that BE supplementation provides moderate protection against Dox‐induced cardiac and hematopoietic damage.
Oral administration of 500 mg/kg of BE for 10 days to mice treated with Dox (10 mg/kg) partially restored the Dox‐induced changes by increasing red blood cell and bone marrow cell counts, and hemoglobin level.
BioFactors  •  2010  |  View Paper