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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Betulinic Acid and Serum Albumin, Human

Research Papers that Mention the Interaction

For the last recent period our lab group reported the high binding affinity of HSA with different phytochemicals including trans-feruloylmaslinic acid, β – sitosterol, N-trans-p-coumaroyltyramine, betulinic acid , L-3,4 dihydroxy phenylalanine and piperine.
Journal of biomolecular structure & dynamics  •  2018  |  View Paper
Further, specifically, the molecular dynamics study makes an important contribution in understanding the effect of the binding of BA on conformational changes of HSA and the stability of the protein-drug complex system in aqueous solution.
In which several cyclohexyl groups of BA are interacting with Phe(206), Arg(209), Ala(210), Ala(213), Leu(327), Gly(328), Leu(331), Ala(350), and Lys(351), residues of sub-domain IIA and IIB of HSA by hydrophobic interactions.
Journal of Molecular Modeling  •  2011  |  View Paper