“For both proteins, we observed that (i) glycine betaine and myo-inositol provide perfect counteraction … 2:1 molar ratio of urea to osmolyte, i.e., denaturing effect of 2M urea is 100% neutralized … 1M of glycine betaine (or myo-inositol), and (ii) sorbitol fails to refold urea denatured proteins.”