Possible Interaction: Betaine and Taurine

“Collectively, our findings indicate that adjuvantial taurine treatment has the potential to significantly improve clinical outcomes …., Jiang, H, Phinney, W. N., Keating, A. K., Hurt, K. J., Stabler, S. P. Taurine alleviates repression of betaine‐… improves the efficacy of long‐term betaine treatment in a mouse …‐synthase‐deficient homocystinuria.”

“ Taurine treatment induced BHMT expression in HCU mice by 5‐fold and restored maximal lowering of Hcy levels during long‐term betaine treatment with a concomitant normalization of inflammatory cytokine expression and a significantly improved coagulative phenotype.”

“ Taurine uptake was about sixfold higher than that of betaine and myo‐inositol.”

“ Betaine and taurine , recently identified as osmolytes in liver cells, interfere with these effects.”

“One case of mixture suppression occurred for a compound Tau ) tha did not produce a current when presented alone but which when added to Bet suppressed the inward current generated by Bet.”

“A synthetic mixture of 21 amino acids plus betaine , which mimics the composition of a natural food stimulus (crab muscle tissue) and itself contains taurine, totally and reversibly blocked the taurine response of this group of receptor cells.”

“Further investigation indicates that betaine and taurine can enhance the quinary interaction between the protein and cellular environment and manifestly weaken the electrostatic attraction in protein salt bridges.”