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“Further analysis shows that betaine supplementation reduced intramyocellular lipid accumulation might be associated with increasing polyunsaturated fatty acids ( PUFA ), fatty acid oxidation, and the inhibition of fatty acid synthesis in muscle.”
“Chronic alcohol (ETOH) and high omega-3 polyunsaturated fatty acids (omega-3 PUFA) consumption may affect PON1 status presumably via reactive oxygen species by depleting liver glutathione (GSH), whereas betaine may counter their effects.”
“Concomitantly, betaine reduced hepatosteatosis accompanied by alleviation of liver injury caused by chronic alcohol and high omega-3 PUFA.”
Alcoholism, clinical and experimental research • 2010 | View Paper
“Increasing dietary PUFA also resulted in a decrease in circulating betaine , dimethylglycine and sarcosine in comparison to the cats consuming the control food at the end of the study.”