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Discover Supplement-Drug Interactions

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Last Updated: 4 years ago

Possible Interaction: Betaine and Glycerylphosphorylcholine

Research Papers that Mention the Interaction

Addition of inositol and/or betaine to the medium greatly increases GPC :PDE activity in cells in isosmotic or high-NaCl media, but the increase is much less in high-urea medium.
Collectively, these data support the conclusion that betaine and/or inositol reduces GPC by increasing GPC degradation catalyzed by GPC:PDE.
We find that MDCK cell GPC content decreases when the cells take up betaine and/or inositol from the medium.
The American journal of physiology  •  1996  |  View Paper
When cell betaine or inositol is increased by raising its concentration in the medium, GPC :PDE activity rises, reducing cell GPC.
Kidney international  •  1996  |  View Paper
The effects of GPC are slightly less than those of betaine.
Kidney international. Supplement  •  1996  |  View Paper