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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Betaine and Folic Acid

supplement:

Betaine

supplement:

Folic Acid

Research Papers that Mention the Interaction

Folic acid supplementation increased betaine concentration in a dose-dependent manner (P for trend = 0.018); the maximum increase (15%) was obtained at daily doses of 400-800 microg/d.
Folic acid supplementation increases the betaine concentration, which indicates that the 2 remethylation pathways are interrelated.
The American journal of clinical nutrition  •  2005  |  View Paper
A further decrease in plasma tHcy by 5 % (P<0·01) was achieved by combining 1 mg folic acid with the 6 g betaine dose.
British Journal of Nutrition  •  2004  |  View Paper