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“Coinjection with 5 mM dimethylamino-ethanol , a choline oxidase inhibitor, and 100 mM cold betaine reduced medullary betaine accumulation by 80 and 76%, respectively.”
The American journal of physiology • 1997 | View Paper
“These data show that DMAE is an effective inhibitor of betaine production by the kidney and, as such, may be an important agent for the study of osmoregulation by the kidney.”