Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 4 months ago

Possible Interaction: Beta-Tocopherol and Vitamin E

supplement:

Beta-Tocopherol

supplement:

Vitamin E

Research Papers that Mention the Interaction

Alpha-tocopherol, but not beta-tocopherol, inhibited smooth muscle cell proliferation and protein kinase C in a dose-dependent manner, at concentrations ranging from 10 to 50 microM. Beta-tocopherol added simultaneously with alpha-tocopherol prevented both proliferation and protein kinase C inhibition.
Prostaglandins, leukotrienes, and essential fatty acids  •  1997  |  View Paper
The effect of alpha-tocopherol and beta-tocopherol on protein kinase C activity and gene expression suggest a cause-to-effect relationship.
Biochemistry and molecular biology international  •  1997  |  View Paper
The phenomenon occurs at concentrations in the range 10-50 microM. beta-tocopherol addition together with alpha-tocopherol , prevents both cell growth and protein kinase C inhibition.
BioFactors  •  1998  |  View Paper
When added together, beta-tocopherol prevents the effects of alpha-tocopherol indicating that the mechanism involved is not related to the radical-scavenging properties of these two molecules, which are essentially equal.
Diabetes research and clinical practice  •  1999  |  View Paper
Furthermore d-beta-tocopherol prevents the inhibition of cell growth and of PKC activity caused by d-alpha-tocopherol.
Proceedings of the National Academy of Sciences of the United States of America  •  1995  |  View Paper
D-beta-Tocopherol , a poor inhibitor of smooth muscle cell proliferation, has been shown to be capable of preventing and reversing the inhibition by D-alpha-tocopherol.
The competition between D-alpha-tocopherol and D-beta-tocopherol suggests the existence of a common binding site for the two molecules.
Archives of biochemistry and biophysics  •  1995  |  View Paper
Concentration of a-tocopherol in colostrum and milk fat was several-fold higher with supplemental dietary vitamin E than without and lard tended to promote a higher concentration than corn oil although the difference was not significant.
Journal of animal science  •  1976  |  View Paper