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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Beta Sitosterol and Serum Albumin, Human

Research Papers that Mention the Interaction

Specifically, the molecular dynamics study makes an important contribution to understanding the effect of the binding of beta-sitosterol on conformational changes of HSA and the stability of a protein-drug complex system in aqueous solution.
The experimental results show that the intrinsic fluorescence of HSA is quenched by addition of beta-sitosterol through a static quenching mechanism.
Upon binding of beta-sitosterol to HSA , the protein secondary structure was partially unfolded.
The journal of physical chemistry. B  •  2010  |  View Paper