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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Beta-Lapachone
supplement:
Genistein
Research Papers that Mention the Interaction
“The overall results indicate that combination treatments with β‐lapachone and genistein are more potent in killing both PC3 and LNCaP cancer cells than treatment with either genistein or β‐lapachone alone.”
“The results showed: i) that both PC3 and LNCaP are sensitive to single and combination treatments regardless of hormone sensitivity status, ii) that … both cell types correlated positively with cell death via apoptosis at lower drug concentrations and necrosis at higher concentrations, iv) that combination of genistein … β‐lapachone ….”
Chemosensitivity of human prostate cancer cells PC3 and LNCaP to genistein isoflavone and β‐lapachone“It was observed that higher doses of both genistein and beta-lapachone significantly suppressed acrosome reaction and that this inhibitory effect was both dose- and time-dependent.”
Toxic potential of dietary genistein isoflavone and beta-lapachone on capacitation and acrosome reaction of epididymal spermatozoa.
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