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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Beta Carotene
supplement:
Zeaxanthin
Research Papers that Mention the Interaction
“The picture is complicated by the fact that folate, lutein/zeaxanthin , and beta-carotene were highly intercorrelated ( r =0.87 to 0.99).”
Diets lower in folic acid and carotenoids are associated with the coronary disease epidemic in Central and Eastern Europe.“Thus, in the presence of high amounts of beta-carotene , there is a preferential uptake of the xanthophylls lutein and zeaxanthin as compared to all-trans beta-carotene from the intestinal lumen into chylomicrons.”
“More importantly, beta-carotene decreased the concentrations of both lutein and zeaxanthin in the plasma and most tissues, including the retina.”
“The retina appears to have the capacity to preserve accumulation of lutein and zeaxanthin , but this capacity is diminished when intake of beta-carotene is high.”
Competitive inhibition of carotenoid transport and tissue concentrations by high dose supplements of lutein, zeaxanthin and beta-carotene
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