Possible Interaction: Beta Carotene and Vitamin C

“In the presence of catechin, a well-known polyphenol found in red wine, ascorbic acid at pH 3.0 works in a synergistic manner preventing lipid peroxidation and beta-carotene cooxidation.”

“CONCLUSION; Antioxidant VE, VC combined with different doses of beta-C supplementation could improve the function of erythrocyte in the elderly subjects.”

“… vitamin C … beta-carotene were inversely associated with the risk of BE (4th vs 1st quartile, adjusted odds ratio [OR] 0.48, 95% confidence interval [CI] 0.….32–0.99, respectively), and the inverse association was strongest for vitamin E (OR 0.25, 95% CI 0.11–0.59).”

“Our results demonstrate that a correlation existed between the levels of serum ascorbic acid and beta carotene , alpha-tocopherol and lipid peroxidation in gastric carcinoma.”

“Significant differences were observed for beta-carotene and vitamin C intake, with an 11% higher intake of beta-carotene and a 12% higher intake of vitamin C in ex-smokers than in current smokers.”

“We found an inverse … the intakes of beta-carotene (OR = 0.67, 95% CI: 0.37-….19, p trend = 0.06) and ascorbic acid (OR = 0.60, 95% CI: 0.33-1.09, p trend = 0.04) … patients, although only the trend for ascorbic acid intake reached statistical significance.”

“ beta-Carotene and ASA may act synergistically to prevent PROM in smokers.”

“ Vitamin C significantly inhibited NO production, enhanced macrophage proliferation and phagocytic activity while vitamin E and beta-carotene had marginal effect.”

“The additive inhibitory influence of beta-carotene and ascorbic acid on endogenous blastomogenesis was not found in mice.”

“The concentration of pigments decreased at longer storage time and increased at higher concentration of ascorbic acid, beta-carotene being more sensitive towards storage time and concentration of ascorbic acid than capsanthin.”