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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Berberine
drug:
Thioguanine
Research Papers that Mention the Interaction
“Using HepG2 human hepatoma cells, we found that BBR inhibits cholesterol and TG synthesis in a similar manner to the AMP-activated protein kinase (AMPK) activator 5-aminoimidazole-4-carboxamide 1-β-ribofuranoside (AICAR).”
Inhibition of lipid synthesis through activation of AMP kinase: an additional mechanism for the hypolipidemic effects of berberine Published, JLR Papers in Press, February 28, 2006.“According to our study, berberine did not only significantly improve 3× Tg AD mice's spatial learning capacity and memory retentions, but also attenuated the hyperphosphorylation of tau.”
“ BBR reduced plasma TG levels by 31% at a marginal significance relative to the control (p=0.054), whereas PS had no effect.”
Co-administration of berberine and plant stanols synergistically reduces plasma cholesterol in rats.“The results showed that BBR ameliorated cognitive deficits in 3× Tg AD mice, reduced the Aβ accumulation, inhibited the apoptosis of neurons, promoted the formation of microvessels in the mouse brain by enhancing brain CD31, VEGF, N-cadherin, Ang-1.”
Berberine Improves Cognitive Impairment by Simultaneously Impacting Cerebral Blood Flow and β-Amyloid Accumulation in an APP/tau/PS1 Mouse Model of Alzheimer’s Disease“Compared with other drugs, berberine alone decreased TG level in NAFLD patients significantly.”
“The subgroup analyses on TG, AST, and FBG indicated that treatment combined with berberine decreased TG level in NAFLD patients significantly.”
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