“Furthermore, the combination of berberine and tamoxifen induced cell growth inhibition more effectively than tamoxifen alone.”
“The results of the present study suggested that berberine may potentially be useful as an adjuvant agent in cancer chemotherapy to enhance the effect of tamoxifen , which will be useful for anti‑tumor therapy and further research.”
“Thus, the aim of the present study was to assess whether berberine enhanced the anticancer effect of tamoxifen , and the underlying mechanism involved in this combined effect in tamoxifen-sensitive (MCF-7) and tamoxifen-resistant (MCF-7/TAM) cells using MTS, flow cytometry and western blot assays.”