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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Berberine and Sphingosine 1-Phosphate

supplement:

Berberine

Research Papers that Mention the Interaction

In OGD-treated neurons, BP enhanced HIF-1[Formula: see text] accumulation with activation of PI3K/Akt, and induced S1P production by activating Sphk2 via the promotion of HIF-1[Formula: see text]-mediated Sphk2 transcription.
The American journal of Chinese medicine  •  2016  |  View Paper
Moreover, BBR was associated with a decrease in SphK1 and S1P levels both in the animals and in culture.
Biochemical and biophysical research communications  •  2017  |  View Paper
Moreover, BBR down-regulated the elevated staining, activity and levels of mRNA and protein of SphK1, and S1P production as well.
Archives of biochemistry and biophysics  •  2010  |  View Paper
Conclusion Berberine exhibited significant antifungal activity in Candida spp.
Drug design, development and therapy  •  2020  |  View Paper