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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Berberine
drug:
Rosuvastatin
Research Papers that Mention the Interaction
“Further in vivo study indicated that berberine plasma exposure could be significantly increased by co-administration of the OATP inhibitor rifampicin or the substrate rosuvastatin.”
Organic anion-transporting polypeptides contribute to the hepatic uptake of berberine“Combination of BBR and rosuvastatin exerted greater effects than BBR or rosuvastatin alone.”
“In HepG2 cells, 10–50 μM berberine significantly increased the uptake of rosuvastatin by inducing the expression of OATP1B1 mRNA and protein.”
Berberine Promotes OATP1B1 Expression and Rosuvastatin Uptake by Inducing Nuclear Translocation of FXR and LXRα
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