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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Berberine and Pyrimethamine



Research Papers that Mention the Interaction

In rats, we found that pyrimethamine (PYR), an inhibitor of Mate1, increased hepatic and renal distribution of BBR and decreased systematic excretion of BBR.
Xenobiotica; the fate of foreign compounds in biological systems  •  2018  |  View Paper
In animal experiments, compared with the berberine alone group, the cumulative urinary excretion of berberine significantly decreased in the corticosterone or pyrimethamine pretreatment groups.
Biopharmaceutics & drug disposition  •  2018  |  View Paper