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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Berberine
drug:
Potassium Chloride
Research Papers that Mention the Interaction
“ Berberine showed significant and concentration-dependent relaxant effects in non-incubated tissues contracted by KCl and methacholine (p<0.01 to p<0.001).”
Histamine (H1) Receptors, Cyclooxygenase Pathway and Nitric Oxide Formation Involved in Rat Tracheal Smooth Muscle Relaxant Effect of Berberine.“Our results showed that chronic administration of 100 mg/kg/day berberine not only reduced glucose levels, but also inhibited the augmented contractile function of cerebral artery to KCl and 5-hydroxytryptamine (5-HT) in diabetic rats.”
“…,Ber inhibited the increased … mmol/L KCl in a dose dependent manner, with a value of IC(50) being 34.09 micromol/L. 30, 100 micromol/L Ber … ACh evoked Ca(2+) (i) elevation in a dose dependent manner either in the presence or absence of extracellular Ca(2+).”
“These results suggest that the major mechanism of berberine consists of an inhibition of calcium entry from extracellular in the second phase induced by both carbachol and KCl.”
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