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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Berberine
drug:
Phenylephrine
Research Papers that Mention the Interaction
“ Berberine (10(-5) M) reduced over by 50% the transient contraction induced by caffeine or phenylephrine in endothelium-denuded rings bathed in Ca(2+)-free Krebs solution.”
“ Berberine produced a rightward shift of the concentration-response curve to phenylephrine and significantly reduced the maximal contractile response to phenylephrine.”
Vasorelaxant and antiproliferative effects of berberine.“In the rabbit aorta, responses to norepinephrine and phenylephrine were both inhibited by berberine with lower affinity than that in the rat aorta.”
“ Berberine (3 x 10(-7) M) significantly inhibited the phasic contraction induced by phenylephrine but, in contrast to verapamil, had no effect on the high potassium-induced contraction.”
“In addition, berberine , like other vasodilators, differently affected the phasic and tonic contractile response elicited by either phenylephrine or high potassium.”
“The anococcygeus muscle response to phenylephrine was competitively inhibited by berberine with a PA2 value of 6.4.”
“The effects of phenylephrine and acetylcholine were blocked by berberine as well as by atropine.”
“The anococcygeus muscle response to phenylephrine was competitively inhibited by berberine with a PA2 value of 6.4.”
“The effects of phenylephrine and acetylcholine were blocked by berberine as well as by atropine.”
“A significant enhancement of antisecretory effect was observed only with the combination of berberine and L-phenylephrine.”
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