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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Berberine
drug:
Pentobarbital
Research Papers that Mention the Interaction
“Pretreatment of animals with … single oral dose of berberine (4 mg/kg) … prolongation of the pentobarbital (60 mg/kg, i.p.)-induced sleeping time as well as increased strychnine (0.3 mg/kg; i.p.)-induced toxicity, suggestive of inhibitory effect on microsomal drug metabolizing enzymes, cytochrome P450s (CYPs).”
Studies on preventive and curative effects of berberine on chemical-induced hepatotoxicity in rodents.
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