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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Berberine and Palmitic Acid

supplement:

Berberine

supplement:

Palmitic Acid

Research Papers that Mention the Interaction

In either HSMCs or AML12 hepatocytes, BBR (5 μM) abolished palmitate acid (PA)-induced increase of CypD protein levels.
Acta Pharmacologica Sinica  •  2020  |  View Paper
Moreover, supplement with citrate acid, palmitic acid , as well as exogenous extracellular vesicles, could rescue the inhibitory effect of berberine on cell proliferation, suggesting that inhibited ACC activity, suppressed fatty acid synthesis and decreased extracellular vesicles production were important mechanisms account for berberine inhibiting cancer cell proliferation.
Life sciences  •  2020  |  View Paper
Addition of ROS blocker, AMPK inhibitor, and palmitic acid significantly reduced the effect of BBR.
Antioxidants & redox signaling  •  2018  |  View Paper
The results indicated that BBR significantly inhibited PA and LPS-induced activation of ER stress and expression of proinflammatory cytokines in macrophages and hepatocytes.
PloS one  •  2020  |  View Paper