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Last Updated: 3 years ago

Possible Interaction: Berberine and Ng-Nitroarginine Methyl Ester

Research Papers that Mention the Interaction

BBR can increase the level of PI3K/Akt/eNOS mRNA and the protein level of PI3K, p-Akt, eNOS and p-eNOS, which can be blocked by PI3K inhibitor (LY294002) and eNOS inhibitor ( l-NAME).
Blockade of PI3K by 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (Ly294002) and blockade of eNOS by l-NAME (NG-Nitroarginine Methyl Ester) attenuates the effect of BBR.
European journal of pharmacology  •  2014  |  View Paper
The relaxant effects of second concentrations of berberine in incubated tissues with L-NAME , its three lower concentration in incubated tissues with chlorpheniramine and its all concentrations in incubated tissues with indomethacin were significantly lower than non-incubated tissues (p<0.05 to p<0.001).
Iranian journal of allergy, asthma, and immunology  •  2019  |  View Paper
Pretreatment with N(G)-nitro-L-arginine methyl ester (L-NAME) or methylene blue reduced the relaxant effect of berberine , and L-arginine (10(-3) M) partially antagonized the effect of L-NAME.
European journal of pharmacology  •  2000  |  View Paper