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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Berberine
drug:
Methotrexate
Research Papers that Mention the Interaction
“Furthermore, MTX cytotoxic activity was markedly enhanced by BBR in vitro using some human cancer cell lines.”
The impact of Keap1/Nrf2, P38MAPK/NF-κB and Bax/Bcl2/caspase-3 signaling pathways in the protective effects of berberine against methotrexate-induced nephrotoxicity.“Our results indicated that BBR might be useful for prevention of the hepatotoxicity induced by MTX via ameliorative effects on biochemical and oxidative stress indices.”
Hepatoprotective effect of berberine against methotrexate induced liver toxicity in rats.
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