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Last Updated: 3 years ago

Possible Interaction: Berberine and Interleukin-10

supplement:

Berberine

Research Papers that Mention the Interaction

Oral … of BBR inhibited the NF-κB signal transduction pathway, reduced the expression of pro-inflammatory cytokines [interleukin (IL)-…, IL-6, interferon-γ, and tumor necrosis factor-α], promoted the expression of anti-inflammatory cytokines ( IL-10 and transforming growth factor-β), and improved the terminal ileum tissue inflammation.
World journal of gastroenterology  •  2019  |  View Paper
Berberine inhibited colonic expression of iNOS, COX-2, IL-1β, IL-6, and TNF-α, but increased IL-10 expression in the colons of TNBS-treated C3H/HeN and C3H/HeJ mice.
European journal of pharmacology  •  2010  |  View Paper
We found that BBR can suppress the expression of pro‐inflammatory genes IL‐6, TGF‐β, and IL‐1β and upregulate anti‐inflammatory gene IL‐10 expression in the mucosa and RAW 264.7 macrophages.
Journal of cellular biochemistry  •  2018  |  View Paper
Meanwhile, berberine significantly decreased the levels of IL-6 and IL-17, and increased the levels of IL-10 and TGF-β.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie  •  2017  |  View Paper
The results showed that a high dose of BER (10 mg/kg) could decrease both the absolute and relative percentages of spleen Treg cells as well as decrease the production of IL-10 by splenocytes in the treated mice (p<0.05).
Journal of acupuncture and meridian studies  •  2017  |  View Paper
And the protein secretion of TGFβ1 was inhibited; however, the protein secretion of IL-10 was increased in cardiac fibroblasts with berberine treatment.
International journal of clinical and experimental pathology  •  2015  |  View Paper
In contrast, interleukin-10 in the mice with berberine treatment was significantly greater than in the control group (p < .01).
International journal of radiation oncology, biology, physics  •  2010  |  View Paper
Berberine produces a significant elevation (P<0.05) in cardiac IL-10 and serum GSH with a significant reduction in (P<0.05) cardiac injury.
Medical archives  •  2021  |  View Paper
The results revealed that berberine treatment downregulated the serum expression of inflammatory factors, including interleukin (IL)-6, tumor necrosis factor-α, IL-10 and IL-17A in mice with anoxia-reoxygenation injury.
Experimental and therapeutic medicine  •  2019  |  View Paper
TLR4, NF-κB, iNOS, TNF-α, IL-6 and IL-10 expression was decreased following berberine intervention.
Experimental and therapeutic medicine  •  2018  |  View Paper
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