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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“In this study, the results of the in vitro model of immunoglobulin (Ig) E-mediated mast cell degranulation showed that berberine significantly inhibited the release of β-hexosaminidase (β-HEX), histamine , IL-4 and TNF-α in rat basophilic leukemia cells (RBL-2H3 cells).”
Berberine suppresses mast cell-mediated allergic responses via regulating FcɛRI-mediated and MAPK signaling.“… berberine significantly attenuated ear swelling in DNFB-induced ACD (ACD vs high dose of berberine 0.48 ± 0.03 vs. 0.33 ± 0.03 … MC recruitment (61 ± 4.07 vs. 39 ± 3.42 mast cells/mm2, P < 0.01), as well as decreased inflammatory cytokine, IgE, and histamine productions (…).”
MicroRNA-21-Mediated Inhibition of Mast Cell Degranulation Involved in the Protective Effect of Berberine on 2,4-Dinitrofluorobenzene-Induced Allergic Contact Dermatitis in Rats via p38 Pathway“ Berberine (25-200 microM) inhibited the response of the strips to norepinephrine and histamine , but did not decrease the high K(+)-elicited contraction.”
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