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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Berberine
drug:
Dextromethorphan
Research Papers that Mention the Interaction
“The pharmacokinetics of dextromethorphan was significantly decreased when the concentration of berberine was exceed 200 microg x L(-1).”
[CYP450 enzyme inhibition of berberine in pooled human liver microsomes by cocktail probe drugs].“Compared with the control group, Dex significantly inhibited cell migration (P < 0.05), while Berb pretreatment could enhance cell migration (P < 0.05).”
“Conclusion Berb attenuated DEX induced reduction of proliferation and migration, oxidative stress, and apoptosis of tendon cells by activating the PI3K/AKT signaling pathway and regulated the expression of phenotype related biomarkers in tendon cells.”
“Methods CCK-8 assay was used … cells and the doses of Berb … Dex cytotoxicity; cell wound healing assay was used to detect the effects (P < 0.05) of Berb and Dex … used to measure cell apoptosis; DCF DA fluorescent probe was used to measure the ROS activity of cells.”
Effects and Mechanism of Berberine on the Dexamethasone-Induced Injury of Human Tendon Cells
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