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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Berberine
drug:
Creatinine
Research Papers that Mention the Interaction
“As compared to MTX-treated group, BBR effectively reduced the serum levels of creatinine , urea, uric acid and kidney/body weight ratio with a remarkable increase in serum level of albumin and the final body weight.”
The impact of Keap1/Nrf2, P38MAPK/NF-κB and Bax/Bcl2/caspase-3 signaling pathways in the protective effects of berberine against methotrexate-induced nephrotoxicity.“ BBR treatment significantly reduced the serum levels of urea and creatinine , retrieved the alterations in kidney histopathology, and restored redox balance evidenced by alleviations of the level of malondialdehyde, 8-hydroxy-2′-deoxyguanosine and activating heme oxygenase-1 enzyme.”
Berberine ameliorates renal injury in a rat model of D‐galactose-induced aging through a PTEN/Akt-dependent mechanism“Glomerular area, glomerular volume, FBG, BUN, Cr and UP24h were significantly decreased in the berberine treatment group compared with the diabetic model group (P < 0.05).”
“In the in vivo experiment, BBR substantially decreased the level of UA, BUN and CRE , and alleviated the kidney damage in mice with HUA.”
Effect of Berberine on Hyperuricemia and Kidney Injury: A Network Pharmacology Analysis and Experimental Validation in a Mouse Model
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