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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
Research Papers that Mention the Interaction
“ Berberine suppressed CPT‑11‑induced NF‑κB … manner and enhanced chemosensitivity to CPT‑11 by downregulating NF‑κB activation of antiapoptotic genes, c‑IAP1, c‑IAP2, survivin and Bcl‑xL. The current … inhibits NF‑κB activation and may be used to enhance CPT‑11‑induced apoptosis in colon cancer.”
Berberine enhances chemosensitivity to irinotecan in colon cancer via inhibition of NF‑κB.“Furthermore, the protein expression levels of SIRT3, p-AMPK, p-ACC, and CPT-1A in the liver were significantly increased in the BBR group as compared with those in the HFD group.”
Berberine Ameliorates High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Rats via Activation of SIRT3/AMPK/ACC Pathway“Combined treatment with berberine and an anti-cancer drug, CPT-11 , resulted in a marked inhibition of tumor growth at the implantation site and of lymphatic metastasis, as compared with either treatment alone.”
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