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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
Research Papers that Mention the Interaction
“In addition, CREB phosphorylation and C/EBPβ expression induced by 3-isobutyl-1-methylxanthine (IBMX) and forskolin were also attenuated by berberine.”
“The binding activities of cAMP responsive element (CRE) stimulated by IBMX and forskolin were inhibited by berberine.”
Berberine Suppresses Adipocyte Differentiation via Decreasing CREB Transcriptional Activity“Prior exposure of adipocytes to berberine decreased the intracellular cAMP production induced by isoproterenol, forskolin , and 3-isobutyl-1-methylxanthine (IBMX), along with hormone-sensitive lipase (HSL) Ser-563 and Ser-660 dephosphorylation, but had no effect on perilipin phosphorylation.”
“On the other hand, berberine produced a leftward shift of the log concentration‐response curves of isoproterenol, forskolin and nitroprusside.”
“ Berberine , applied to the basolateral bathing solution, also reduced SCC responses to the following agents which stimulate chloride secretion in rat colon: carbachol, forskolin , sodium nitroprusside, dibutyryl cyclic‐AMP, heat‐stable E. coli enterotoxin, 8‐bromo‐cyclic GMP and thapsigargin.”
“ Berberine decreased forskolin-induced short-circuit current in a concentration-dependent manner (IC50 80 ± 8 μM).”
Berberine Reduces cAMP-Induced Chloride Secretion in T84 Human Colonic Carcinoma Cells through Inhibition of Basolateral KCNQ1 Channels
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