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Discover Supplement-Drug Interactions

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Last Updated: 5 years ago

Possible Interaction: Berberine and Clarithromycin

supplement:

Berberine

Research Papers that Mention the Interaction

“3) When cells were perfused concomitantly with Berberine and Clarithromycin , they showed a stronger inhibitive effect on hERG currents by decreasing the time constant for the onset of inactivation. (”
“4) The combined administration of Berberine with Clarithromycin had a powerful inhibitive effect on CYP3A activities than use of a single drug alone.”
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences  •  2015  |  View Paper
“The minimum inhibitory concentration (MIC) of clarithromycin showed at least a fourfold reduction in presence of BER (83% of total isolates), CCCP (67%), PIP (25%) and TET (75%).”
The Journal of Antibiotics  •  2019  |  View Paper
“Similarly, ½ × MIC berberine had a significant effect on the MIC reductions of nine antibiotics including TMP/SXT, CLA , and LZD.”
Evidence-based complementary and alternative medicine : eCAM  •  2020  |  View Paper