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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Berberine
drug:
Atorvastatin
Research Papers that Mention the Interaction
“Combination therapy with BBR and atorvastatin was more effective in preventing atherosclerotic processes than atorvastatin alone.”
“The results obtained in the present study demonstrate that the combination of atorvastatin and BBR is more effective in inhibiting foam cell formation than using atorvastatin alone.”
The anti-atherogenic effects of berberine on foam cell formation are mediated through the upregulation of sirtuin 1.“ Berberine combined with atorvastatin also decreased serum total cholesterol (TC), triglyceride (TG) and low‑density lipoprotein‑cholesterol (LDL‑C) levels in the rat model as well as inflammation and oxidative stress.”
“Furthermore, plasma ET‑1 levels and LOX‑1 expression were decreased by berberine combined with atorvastatin treatment, and the inhibitory effect on LOX‑1 was impeded by an ET‑1 receptor antagonist.”
“The results demonstrated that berberine combined with atorvastatin downregulates LOX‑1 expression through ET‑1 receptors in monocyte/macrophages in vitro and in vivo.”
Berberine combined with atorvastatin downregulates LOX‑1 expression through the ET‑1 receptor in monocyte/macrophages.
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