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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Benzocaine
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“It is concluded that benzocaine not only exerts an indirect action on the membrane permeability to calcium but also affects key steps of the Ca-ATPase enzymatic cycle.”
Drug action of benzocaine on the sarcoplasmic reticulum Ca-ATPase from fast-twitch skeletal muscle“LA's which are esters of p-aminobenzoic acid (including benzocaine ), or which possess either an amide group (dibucaine), an amidine group (phenacaine), or an amino alkyl ether linkage (diphenhydramine) all produced a graded inhibition of the action of calcium , which was reversed by excess calcium (3 mM).”
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