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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Benserazide
supplement:
Tryptophan
Research Papers that Mention the Interaction
“… L-tryptophan , tetrahydropteridine:oxygen oxidoreductase [5-hydroxylating]; EC 1.14.16.4; TPH), the initial …-limiting enzyme in the biosynthesis of the neurotransmitter serotonin, was inhibited directly by benserazide , an inhibitor of aromatic-L-amino-acid decarboxylase (3,4-…-L-phenylalanine carboxy-lyase; EC 4.1.1.28; AAAD).”
Inhibition of tryptophan hydroxylase by benserazide and other catechols.“It may be possible to potentiate the therapeutic effect of tryptophan by administering it with benserazide to inhibit its peripheral catabolism through the pyrrolase pathway.”
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