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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Benserazide and Tryptophan

supplement:

Tryptophan

Research Papers that Mention the Interaction

… L-tryptophan , tetrahydropteridine:oxygen oxidoreductase [5-hydroxylating]; EC 1.14.16.4; TPH), the initial …-limiting enzyme in the biosynthesis of the neurotransmitter serotonin, was inhibited directly by benserazide , an inhibitor of aromatic-L-amino-acid decarboxylase (3,4-…-L-phenylalanine carboxy-lyase; EC 4.1.1.28; AAAD).
Biochemical pharmacology  •  1991  |  View Paper
It may be possible to potentiate the therapeutic effect of tryptophan by administering it with benserazide to inhibit its peripheral catabolism through the pyrrolase pathway.
Biochemical pharmacology  •  1978  |  View Paper