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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Benserazide
supplement:
Melatonin
Research Papers that Mention the Interaction
“Therefore benserazide inhibits melatonin synthesis in the rodent but not in humans with the conventional doses used in the treatment of Parkinson's disease.”
Atypical meningitis complicating a penetrating head injury.“Therefore benserazide inhibits melatonin synthesis in the rodent but not in humans with the conventional doses used in the treatment of Parkinson's disease.”
“It is concluded that benserazide probably inhibits melatonin synthesis by preventing the formation of the substrate, 5-hydroxytryptamine.”
Effect of benserazide on the levels of pineal 5-hydroxytryptamine, melatonin synthesising enzymes and serum melatonin.“1 Low doses (50 and 80 mg/kg) of benserazide (Ro4‐4602), an aromatic amino acid decarboxylase inhibitor, markedly reduced 5‐hydroxytryptamine and melatonin in the rat pineal gland without affecting hypothalamic 5‐hydroxytryptamine.”
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