supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Bemegride
supplement:
Gamma-Aminobutyric Acid
Research Papers that Mention the Interaction
“ Bemegride had an antagonistic action on the GABAA receptor, suppressing both GABA‐ and pentobarbitone‐evoked whole‐cell currents to similar extents.”
Actions of steroids and bemegride on the GABAA receptor of mouse spinal neurones in culture“4 Bemegride and leptazol both antagonized GABA , but with low potency and in a manner which was clearly not competitive.”
“ Bemegride , 800 nmoles, reduced reversibly the inhibitory actions of glutamate and acetylcholine but potentiated irreversibly both responses to GABA.”
“(-)-Bicuculline methochloride, leptazol and bemegride antagonized GABA or glycine in less than 10% of experiments, although (-)-bicuculline methochloride excited most neurones.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback