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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Becaplermin
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“Our results indicate that high concentrations of calcium (Ca) and thrombin (Thr) trigger an immediate and significant increase in bFGF, TGF-beta 1 and PDGF-BB concentrations.”
Effects of calcium and thrombin on growth factor release from platelet concentrates: kinetics and regulation of endothelial cell proliferation.“In conclusion, atorvastatin calcium inhibits phenotype modulation of PDGF-BB-induced VSMCs and activation of the Akt signaling pathway, indicating that Akt might play a vital role in the modulation of phenotype.”
“Treatment of VSMCs with atorvastatin calcium showed dose-dependent inhibition of PDGF-BB-induced proliferation.”
Atorvastatin Calcium Inhibits Phenotypic Modulation of PDGF-BB-Induced VSMCs via Down-Regulation the Akt Signaling Pathway“The phosphorylation of MARCKS mediated by rPDGF-BB was significantly reduced by each CA.”
“In particular, PDGF-BB and PDGF-AB but not PDGF-AA could elicit alterations in cytosolic free calcium (Ca2+i).”
“ PDGF-BB elicited monophasic alterations in Ca2+i in both thoracic and abdominal VSMC.”
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