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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Bcg Vaccine and Dehydroepiandrosterone

Research Papers that Mention the Interaction

Androgens in males and DHEA overdose might reduce the efficacy of BCG.
However, the addition of high dose (0.1%) DHEA decreased the efficacy of high dose (2 × 105 CFUs) BCG in suppressing the airway responsiveness and eosinophilia.
In conclusion, the combination of low doses of BCG and DHEA had an additive effect in suppressing the development of airway hypersensitivity.
In female mice, the combined … of 2 × 104 CFUs BCG and ….01% DHEA effectively suppressed the ovalbumin-induced increase in airway sensitivity to methacholine (56.5 vs. 8.2 mg/mL, p < 0.01), while BCG (13.9 mg/mL) or DHEA (17.9 mg/mL) alone did not.
Immunological investigations  •  2008  |  View Paper
Androgens in males and dehydroepiandrosterone overdose might reduce the efficacy of BCG.
In conclusion, treatment with an appropriate combination of BCG and dehydroepiandrosterone had additive therapeutic effects on mice with established asthma.
Experimental lung research  •  2009  |  View Paper