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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Barbital and Epinephrine



Research Papers that Mention the Interaction

Recently, Mazel et al. (4) reported that epinephrine increased the brain level of barbital above controls and suggested that epinephrine may affect the permeability of the blood-brain barrier as well as other barriers.
Japanese journal of pharmacology  •  1970  |  View Paper
2) Epinephrine contributes to a greatly increased rate of onset and intensity of ‘anesthesia’ by some mechanism(s) in addition to increasing the rate of entry of barbital into the brain.
Animals receiving barbital with epinephrine displayed immediate signs of depression and became anesthetized much sooner than controls.
Biochemical pharmacology  •  1969  |  View Paper