supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Barbital
supplement:
Epinephrine
Research Papers that Mention the Interaction
“Recently, Mazel et al. (4) reported that epinephrine increased the brain level of barbital above controls and suggested that epinephrine may affect the permeability of the blood-brain barrier as well as other barriers.”
Mechanism of potentiating action of epinephrine on thiopental anesthesia.“2) Epinephrine contributes to a greatly increased rate of onset and intensity of ‘anesthesia’ by some mechanism(s) in addition to increasing the rate of entry of barbital into the brain.”
“Animals receiving barbital with epinephrine displayed immediate signs of depression and became anesthetized much sooner than controls.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback