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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“At the postsynaptic site, baclofen increases potassium conductance, leading to neuronal hyperpolarization.”
Chirality counts?“Bath application of baclofen (10-30 microM) elicited hyperpolarization associated with an increase in potassium conductance in morphologically different types of neurons including putative excitatory and inhibitory neurons.”
Postsynaptic and presynaptic GABAB receptor-mediated inhibition in rat superficial superior colliculus neurons“4 Hyperpolarizations induced by baclofen were associated with an increased inwardly rectifying potassium conductance.”
“6 These studies demonstrate that baclofen acting on GABAB receptors increases potassium conductance in all lateral and ventrolateral periaqueductal gray neurones.”
“This action of GABA and baclofen involves an increase in potassium conductance27.”
“We have shown previously that these latter effects are secondary to the action of baclofen to increase the potassium conductance of neocortical neurons.”
“Both serotonin and the selective gamma-aminobutyric acidB (GABAB) agonist, baclofen , increase potassium (K+) conductance in hippocampal pyramidal cells.”
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