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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Baclofen and Glutamate

supplement:

Glutamate

Research Papers that Mention the Interaction

Both the selective GABA(A) receptor agonist muscimol, and the GABA(B) agonist baclofen strongly inhibited the post-synaptic response to L-glutamate.
Neurobiology of Disease  •  2010  |  View Paper
The SP response was reduced by about 80%, whereas the responses to acetylcholine and glycine were not appreciably affected, and those to L-glutamate , GABA and noradrenaline were depressed by 10-22% by baclofen.
The Journal of experimental biology  •  1980  |  View Paper