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Discover Supplement-Drug Interactions

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Last Updated: 5 years ago

Possible Interaction: Baclofen, (S)- and Adrenocorticotropic Hormone

Research Papers that Mention the Interaction

Previous experiments have shown that the GABAB receptor agonist L-baclofen given subcutaneously to male rats significantly enhanced plasma concentrations of adrenocorticotropic hormone (ACTH) and the adrenocortical hormones corticosterone and aldosterone.
The stimulatory effect of L-baclofen on ACTH , corticosterone and aldosterone was significantly reduced by 60% after pretreatment with CGP 35 348.
The Journal of Steroid Biochemistry and Molecular Biology  •  1993  |  View Paper