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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Aztreonam
supplement:
Epigallocatechin Gallate
Research Papers that Mention the Interaction
“Accumulation assay data suggest that the mechanism of synergy may be due to EGCG increasing the uptake of aztreonam.”
“… aztreonam … EGCG exists [fractional inhibitory concentration indices (FICIs) 0.02-0.5], with the combination affording significantly (P=<0.05) enhanced bacterial killing, with a >3 … to restore susceptibility to aztreonam to a level equal to or below the breakpoint set by the European Committee for Antimicrobial Susceptibility Testing.”
Restoring the activity of the antibiotic aztreonam using the polyphenol epigallocatechin gallate (EGCG) against multidrug-resistant clinical isolates of Pseudomonas aeruginosa.
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