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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Azathioprine and Niacin



Research Papers that Mention the Interaction

We found that nicotinamide prevented UV-induced cellular ATP loss and protected against UV-induced glycolytic blockade.
Photochemistry and photobiology  •  2010  |  View Paper
A hypothesis is discussed which relates the inhibition of RNA synthesis by nicotinamide to a competition resulting from the utilization of ATP both for DPN synthesis and for the formation of nucleoside triphosphates and of RNA in the cell nucleus.
Cancer research  •  1962  |  View Paper
NA inhibits this enzyme, preventing depletion of NAD(+) and ATP in cells exposed to STZ.
Experimental biology and medicine  •  2012  |  View Paper
Newly synthesized compounds, namely, platinum and palladium metal complexes based on substituted pyridinecarboxylic acids inhibit both active transport of Ca ions and hydrolysis of ATP , catalyzed by sarcoplasmic reticulum Ca(2+)-ATPase.
Biomeditsinskaia khimiia  •  2006  |  View Paper
Niacin replenishes the NAD and ATP depletion caused by reactive oxygen species.
Archives of Toxicology  •  2004  |  View Paper
Alternatively, using nicotinamide as a PARP inhibitor restored ATP levels up to 72%.
Taken together, the results show that nicotinamide offers a substantial protective role in terms of preservation of cellular ATP and mitochondrial NAD-linked respiration.
Pharmacology  •  2003  |  View Paper
The PARS inhibitors 3-aminobenzamide (1 mmol/L), nicotinamide (1 mmol/L), and PD 128763 (100 mumol/L) inhibited the reduction in cellular NAD+ and ATP and the suppression of mitochondrial respiration in response to LPS and IFN-gamma stimulation.
Circulation research  •  1996  |  View Paper
Long-term exposure to nicotinamide decreased glucose oxidation and ATP content in the islets.
Diabetologia  •  1986  |  View Paper
A large depletion of intracellular ATP , associated with a marked accumulation of NAD, occurred in slices in response to the addition of high amounts of nicotinamide.
Biochimica et biophysica acta  •  1984  |  View Paper